Mingfeng Bai, PhD
Assistant Professor

Medical/Graduate School Vanderbilt University, MS
Vanderbilt University, PhD
Clinical/Post-doctoral Fellowship Washington University in St. Louis School of Medicine (Post-doctoral)
& Programs
Clinical Interest Molecular Imaging of Cancers, Alzheimer's Disease and Immune System.
Research Interest Contrast agents development and preclinical optical imaging
Selected Publications   Shaojuan Zhang, Ling Yang, Xiaoxi Ling, Pin Shao, Xiaolei Wang, W. Barry Edwards, Mingfeng Bai Tumor Mitochondria-targeted Photodynamic Therapy with a Translocator Protein (TSPO)-specific Photosensitizer Acta Biomaterialia 2015, accepted.

Xiaoxi Ling, Shaojuan Zhang, Pin Shao, Pengcheng Wang, Xiaochao Ma and Mingfeng Bai Synthesis of a reactive oxygen species responsive heterobifunctional thioketal linker Tetrahedron Letters 2015, 56(37), 5242-5244.

Xiaoxi Ling, Shaojuan Zhang, Pin Shao, Weixia Li, Ling Yang, Ying Ding, Cong Xu, Nephi Stella, and Mingfeng Bai A Novel Near-infrared Fluorescence Imaging Probe that Preferentially Binds to Cannabinoid Receptors CB2R over CB1R Biomaterials 2015, 57: 169-178.

Yun Zeng, Yang Liu, Jin Shang, Jingwen Ma, Rong Wang, Lei Deng, Youmin Guo, Fan Zhong, Mingfeng Bai, Shaojuan Zhang, Daocheng Wu. Phosphorescence Monitoring of Hypoxic Microenvironment in Solid-Tumors to Evaluate Chemotherapeutic Effects Using the Hypoxia-Sensitive Iridium (III) Coordination Compound PLOS ONE 2015, 10(3): e0121293.

Shaojuan Zhang, Pin Shao, Xiaoxi Ling, Ling Yang, Weizhou Hou, Steve H. Thorne, Wissam Beaino, Carolyn J. Anderson, Ying Ding and Mingfeng Bai. In Vivo Inflammation Imaging Using a CB2R-targeted Near Infrared Fluorescent Probe American Journal of Nuclear Medicine and Molecular Imaging 2015, 5(3): 246-258.

Yi Wen, Wen Liu, Christina Bagia, Shaojuan Zhang, Mingfeng Bai, Jelena M. Janjic, Nick Giannoukakis, Ellen S. Gawalt, and Wilson S. Meng. Antibody-Functionalized Peptidic Membranes for Neutralization of Allogeneic Skin Antigen-Presenting Cells Acta Biomaterialia 2014, 10(11) 4759-4767.

Zhiyuan Wu, Pin Shao, Shaojuan Zhang and Mingfeng Bai Molecular Imaging of Human Tumor Cells that Naturally Overexpress Type 2 Cannabinoid Receptors Using a Novel Quinolone-based Near Infrared Fluorescent Probe The Journal of Biomedical Optics 2014, 19(7) 076016.

Ningyang Jia, Shaojuan Zhang, Pin Shao, Christina Bagia, Jelena M. Janjic, Ying Ding and Mingfeng Bai Cannabinoid CB2 Receptor as a New Phototherapy Target for Inhibition of Tumor Growth Molecular Pharmaceutics, 2014, 11(6) 1919-1929.

Pin Shao, Ningyang Jia, Shaojuan Zhang, and Mingfeng Bai Synthesis and Optical Properties of Water-Soluble Biperylene-based Dendrimers ChemComm, 2014, 50(42) 5648-5651.

Jelena M. Janjic, Pin Shao, Shaojuan Zhang, Sravan Kumar Patel, Xun Yang and Mingfeng Bai Perfluorocarbon Nanoemulsions with Fluorescent, Colloidal and Magnetic Properties Biomaterials 2014, 35(18) 4958-4968.

Zhiyuan Wu, Pin Shao, Shaojuan Zhang, and Mingfeng Bai Targeted Zwitterionic Near Infrared Fluorescent Probe for Improved Imaging of Type 2 Cannabinoid Receptors The Journal of Biomedical Optics 2014, 19(3):36006.

Shaojuan Zhang, Ningyang Jia, Pin Shao, Qin Tong, Xiangqun Xie and Mingfeng Bai Target-Selective Phototherapy Using a Ligand-Based Photosensitizer for Type 2 Cannabinoid Receptor Chemistry & Biology 2014, 21(3), 338-344. (Highlighted by Nature SciBX)

Lynn E. Samuelson, Bernard M. Anderson, Mingfeng Bai, Madeline J Dukes, Colette R. Hunt, Jonathon D. Casey, Zeqiu Han, Vassilios Papadopoulos, and Darryl J. Bornhop. A self-internalizing mitochondrial TSPO targeting imaging probe for fluorescence, MRI and EM RSC Advances 2014, 4, 9003-9011.

Shaojuan Zhang, Pin Shao and Mingfeng Bai. In Vivo Type 2 Cannabinoid Receptor-Targeted Tumor Optical Imaging Using a Near Infrared Fluorescent Probe Bioconjugate Chemistry 2013, 24(11), 1907-1916.

James J. Burston, Devi R. Sagar, Pin Shao, Mingfeng Bai, Emma King, Louis Brailsford, Jenna M. Turner, Gareth J. Hathway, Andrew J. Bennett, David A. Walsh, David A. Kendall, Aron H. Lichtman, and Victoria Chapman. Cannabinoid CB2 receptors regulate central sensitization and pain responses associated with osteoarthritis of the knee joint PLOS ONE 2013, 8(11), e80440.
Honors and  
PubMed Publications   See a listing of publications on PubMed, a service of the National Library of medicine.